After a false start with Isis bras (I tried the Henna Day Bra, but the material that sits between the hooks and skin was too thin and the hooks scratched me through it), I'm really happy with this bra. I am very asymmetrical - a C cup on one side and an A on the other, so finding bras that fit can be major pain in the butt. But the stretchy fabric provides a great fit on both sides. I would say this bra is just barely supportive enough for C cups, and I would stick with a traditional bra for dressier occasions. However, it'll be great for casual wear, yoga, and hiking. I'm going to start replacing all of my Patagonia Active Mesh bras with these - the ISIS Active bras provide the same support but with a lot less fabric, and they're so much cuter.
My one complaint is that the chest band rolls up a bit on me. It's a little irritating, but otherwise it doesn't seem to affect the function of the bra at all.