I bought the Eagle Creek Carryon ES for business trips when I wanted to travel with one item of hand luggage only. It's just the right size for a few shirts, a spare pair of trousers and a sweater. I use an Eagle Creek Pack-it folder to keep everything neat (size 18 just fits). It keeps the weight down by not having wheels etc. The pockets are very well thought out and useful for small items. The section for a laptop is not specially padded, so I put my laptop in a padded sleeve before putting it in the bag. If you're careful not to overstuff it, it will fit in the overhead luggage locker of an Embraer 145 (a regional jet with small overhead bins). For me, this is an excellent bag for business trips of up to 5 days, but I travel light.